Search results for "Antimicrobial drug resistance"

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NDM-1 and OXA-163 producing Klebsiella pneumoniae isolates in Cairo, Egypt, 2012

2013

Here we describe carbapenem resistance determinants in two Klebsiella pneumoniae isolates recovered from two hospitalised patients in the same intensive care unit of a cancer hospital in Cairo, Egypt. PCR and sequencing were used to detect and characterise β-lactamase genes. Clonal relationships between the isolates were analysed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). The first K. pneumoniae isolate carried the blaNDM-1 gene and the second isolate carried the blaOXA-163 gene. Both isolates co-expressed the extended-spectrum β-lactamase CTX-M-15. The two isolates belonged to different sequence types (STs), ST11 and ST16, respectively. No history of …

Microbiology (medical)Antimicrobial drug resistanceSettore MED/07 - Microbiologia E Microbiologia ClinicaOXA-163biologyGeographic areaKlebsiella pneumoniaeImmunologyNorth africaSequence typesNDM-1biology.organism_classificationMicrobiologyVirologyMicrobiologyCarbapenemaseKlebsiella pneumoniaeNDM-1; OXA-163; Carbapenemase; Klebsiella pneumoniae; Antimicrobial drug resistancePulsed-field gel electrophoresisImmunology and AllergyMultilocus sequence typingCarbapenem resistance
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